Projects
Institute for Chemistry and Biotechnology
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USP development with CHO cells
CDR-Life is a biotechnology company pioneering a new and differentiated class of highly tumor-specific immuno-oncology therapeutics based on its proprietary antibody-based T cell engager technology. The collaboration between the competence center for Biochemical Engineering and Cell Cultivation Technique at ZHAW and ...
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Valorisation of industrial residues for a sustainable industry (VARESI)
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Development of new therapeutic approaches for the treatment of cancer
Further therapeutic approaches are urgently needed for the treatment of cancer. The aim of this project is to synthesize active substances that interact with biological target proteins relevant in cancer therapy. For this purpose, multi-step organic syntheses are carried out and the active substances are optimized ...
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Process development and biomass production of S. cerevisiae spiked with heavy water
In this project, process development, media optimization, and scale-up of yeasts of the genus S. cerevisiae are investigated. The aim is to achieve maximum biomass yield.
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Development of novel tablet formulations for the detection of pathogenic bacteria
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Developing a gasotransmitter based treatment for pathological skin and tendon calcification
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Evaluation of cell separation using the GEA kytero® Single Use Pharma Separator with disk stack technology
Recently, GEA Westfalia Separator Group GmbH presented a single-use disc separator for microbial as well as mammalian cell culture processes. By using centrifugal force instead of filter-based harvesting methods, the GEA kytero® Single Use Pharma Separator is intended to achieve high-quality and high-yield ...
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Muscle generator – The key to unlock scalable and affordable cultivated meat production
A tissue bioreactor and a corresponding process are developed to enable the differentiation of bovine satellite cells on a proprietary scaffold technology to produce cultured meat. Key to success is the integration of a mechanism to periodically stretch the scaffold/cells to enhance taste & texture. ...
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CFD industrial scale protein extraction
Computational Fluid Dynamics simulation for an extraction processMixing and fluid flow will by analysized and an optimzed process and/or mixing design is to be suggested.
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PURAMMON (Pre-Project) – Renewable nitrogen mineral fertiliser from liquid manure
Substrates heavily polluted with ammonium, such as pig manure, digestate from biogas plants or process water from the protein-processing industry, emit unpleasant odours and contribute significantly to nitrogen emissions (NH3-N) into the atmosphere. Many of these substrates accumulate decentrally and/or seasonally. ...
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Evaluation of Cafetto cleaning protocols for porta filter & automatic coffee machines
Evaluate impact of Cafetto cleaning protocol for coffee machines and grinder on sensory quality of espresso.
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Plants and Minerals in Byzantine Popular Pharmacy. A New Multidisciplinary Approach
Historical texts containing information of the medicinal use of plants, minerals and other natural products are highly interesting study objects for various disciplines, in sciences as well as in humanities. In particular, historical texts can provide rewarding starting points for natural product drug discovery, as ...
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Degassing of Coffee
Modelling degassing of coffee.
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CarboPHOS – Phosphorous recovery through hydrothermal carbonisation of sewage sludge
CarboPHOS develops a technological solution for the recovery of phosphorus from sewage sludge using the hydrothermal carbonization process. An overview of the availability of P-species in Swiss sludges is being compiled and the technology chain HTC - filtration - crystallization is demonstrated in pilot scale. ...
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Development of small-molecules targeting CD93-signaling for the treatment of leukemia
The aim of the current InnoSuisse application is to optimize small molecules, which were identified in a drug library screen to block CD93-signaling in LSCs and showed a positive clinical response, in order to develop lead candidates with a novel chemical scaffold and own IP to treat leukemia. ...
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Miele - Benchmarking of Full Automatic Coffee Machines
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Biocatalytic halogenation for the sustainable development of agrochemicals
The biological activity of agrochemicals is often modulated by the introduction of halogen atoms. To develop sustainable processes for the regio- and stereoselective halogenation of abundant bio-renewable starting materials, the development of tailored biocatalysts is targeted.
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Dynamik Knowledge Platform
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Density of green coffee beans
Develop experimental method of measure the real density of green bean (ZHAW)
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Local Colours – Industrial Natural Dyeing based on plant dyes from waste
The Local Colours project aims to sustainably dye local textiles with natural dyes from local plant waste or plants. The sustainable dyeing of textiles on an industrial scale is the core of the project, which uses the advances in chemistry without depleting fossil resources. The aim is a circular economic approach, ...