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PD Dr. René Köffel

PD Dr. René Köffel

PD Dr. René Köffel

ZHAW School of Life Sciences and Facility Management
Hämatologie & Immunologie

+41 (0) 58 934 57 15
rene.koeffel@zhaw.ch

Work at ZHAW

Position

Head of the Hematology and Immunology group, Lecturer for Bachelor studies in Biomedical Laboratory Diagnostics

Network

Membership of networks

Biotechnet

ORCID digital identifier

ORCID ID: 0000-0001-9477-4282

Social media

Linkedin

Other publications

  • Publications total
  • Besançon H, Larpin Y, Babiychuk VS, Köffel R, Babiychuk EB. Engineered Liposomes Protect Immortalized Immune Cells from Cytolysins Secreted by Group A and Group G Streptococci. Cells. 2022 Jan 5;11(1):166. doi: 10.3390/cells11010166. PMID: 35011729; PMCID: PMC8749993.
  • Besançon H, Babiychuk V, Larpin Y, Köffel R, Schittny D, Brockhus L, Hathaway LJ, Sendi P, Draeger A, Babiychuk E. Tailored liposomal nanotraps for the treatment of Streptococcal infections. J Nanobiotechnology. 2021 Feb 15;19(1):46. doi: 10.1186/s12951-021-00775-x. PMID: 33588835; PMCID: PMC7885208.
  • Borek I, Köffel R, Feichtinger J, Spies M, Glitzner-Zeis E, Hochgerner M, Sconocchia T, Krump C, Tam-Amersdorfer C, Passegger C, Benezeder T, Tittes J, Redl A, Painsi C, Thallinger GG, Wolf P, Stary G, Sibilia M, Strobl H. BMP7 aberrantly induced in the psoriatic epidermis instructs inflammation-associated Langerhans cells. J Allergy Clin Immunol. 2020 Apr;145(4):1194-1207.e11. doi: 10.1016/j.jaci.2019.12.011. Epub 2019 Dec 21. PMID: 31870764.
  • Larpin Y, Besançon H, Iacovache MI, Babiychuk VS, Babiychuk EB, Zuber B, Draeger A, Köffel R. Bacterial pore-forming toxin pneumolysin: Cell membrane structure and microvesicle shedding capacity determines differential survival of cell types. FASEB J. 2020 Jan;34(1):1665-1678. doi: 10.1096/fj.201901737RR. Epub 2019 Dec 4. PMID: 31914676.
  • Köffel R, Wolfmeier H, Larpin Y, Besançon H, Schoenauer R, Babiychuk VS, Drücker P, Pabst T, Mitchell TJ, Babiychuk EB, Draeger A. Host-Derived Microvesicles Carrying Bacterial Pore-Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses. Front Immunol. 2018 Jul 27;9:1688. doi: 10.3389/fimmu.2018.01688. PMID: 30100903; PMCID: PMC6072879.