Dr. Thomas Schwander

Education and Continuing education

Education

• Doctor of Natural Sciences (Dr. rer. nat.) / Biochemistry
  Max Planck Institute for Terrestrial Microbiology
  11 / 2014 - 01 / 2018
• Master of Sciences (M.Sc.) / Microbiology and Immunology
  ETH Zurich
  09 / 2012 - 04 / 2014
• Bachelor of Sciences (B.Sc.) / Biology (chemical major)
  ETH Zurich
  09 / 2009 - 10 / 2012

Network

ORCID digital identifier

ORCID ID: 0000-0001-9201-3017

Social media

LinkedIn

Projects

• National Competence Center of Research Catalysis / Deputy project leader / laufend
• Microbial Epimerases: A Toolbox for the Synthesis of Novel Peptide-Based Drugs / Team member / abgeschlossen

Publications

• Patsch, David; Schwander, Thomas; Voss, Moritz; Schaub, Daniela; Hüppi, Sean; Eichenberger, Michael; Stockinger, Peter; Schelbert, Lisa; Giger, Sandro; Peccati, Francesca; Jiménez-Osés, Gonzalo; Mutný, Mojmír; Krause, Andreas; Bornscheuer, Uwe T.; Hilvert, Donald; Buller, Rebecca M.,

  2024.

  Enriching productive mutational paths accelerates enzyme evolution.

  Nature Chemical Biology.

  20(12), pp. 1662-1669.

  Available from: https://doi.org/10.1038/s41589-024-01712-3

• Eichenberger, Michael; Schwander, Thomas; Hüppi, Sean; Kreuzer, Jan; Mittl, Peer R. E.; Peccati, Francesca; Jiménez-Osés, Gonzalo; Naesby, Michael; Buller, Rebecca M.,

  2023.

  The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis.

  Nature Catalysis.

  6(10), pp. 927-938.

  Available from: https://doi.org/10.1038/s41929-023-01018-y

Publications before appointment at the ZHAW

• Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO2 fixation. PNAS (2014)
• A synthetic pathway for the fixation of carbon dioxide in vitro. Science (2016)
• Molecular Basis for Converting (2S)-Methylsuccinyl-CoA Dehydrogenase into an Oxidase. Molecules (2018)
• Structural basis for substrate specificity of methylsuccinyl-CoA dehydrogenase, an unusual member of the acyl-CoA dehydrogenase family. JBC (2018)
• Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts. Science (2020)
• Exploring alternative pathways for the in vitro establishment of the HOPAC cycle for synthetic CO 2 fixation. Science Advances (2023)

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