In-depth molecular analysis of stool and water samples collected in Kampala, Uganda
Description
A novel approach, combining next-generation sequencing and comparison to custom databases is being tested to assess the impact of wastewater use in agriculture in the city of Kampala, Uganda. The overarching goal of this project is to bring epidemiological studies, classically targeting only one or a few pathogens to a whole new level by combining the analysis of resistance mechanisms as well as the identification of almost all known pathogens using only one experimental approach.
Key Data
Projectlead
Project partners
National Water and Sewerage Corporation NWSC; Government of Uganda / Ministry of Health; Schweizerisches Tropen- und Public Health-Institut; Universität Basel; Bundesamt für Bevölkerungsschutz BABS / Labor Spiez; Agroscope
Project status
completed, 05/2013 - 04/2017
Funding partner
Internal
Publications
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Qualitative microbiome profiling along a wastewater system in Kampala, Uganda
2019 Schneeberger, Pierre H. H.; Fuhrimann, Samuel; Becker, Sören L.; Pothier, Joël F.; Duffy, Brion; Beuret, Christian; Frey, Jürg E.; Utzinger, Jürg
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Development and evaluation of a bioinformatics approach for designing molecular assays for viral detection
2017 Schneeberger, Pierre H.H.; Pothier, Joël F.; Bühlmann, Andreas; Duffy, Brion; Beuret, Christian; Utzinger, Jürg; Frey, Jürg E.
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Metagenomic diagnostics for the simultaneous detection of multiple pathogens in human stool specimens from Côte d’Ivoire : a proof-of-concept study
2016 Schneeberger, Pierre H.H.; Becker, Sören L.; Pothier, Joël F.; Duffy, Brion; N'Goran, Eliézer K.; Beuret, Christian; Frey, Jürg E.; Utzinger, Jürg
