PRIME aims to create new solutions for deployment by SMEs of highly adaptive, re-configurable self-aware plug and produce assembly systems, which will use multi-agent control,dynamic knowledge sharing, integrated monitoring, and innovative human-machine interaction mechanisms. These next generation assembly systems equipped with PRIME technology will be able to proactively support rapid reconfiguration, adaptation, error-recovery, and operational performance improvement. This will lead to a dramatic cost and time reduction of deploying and maintaining complex assembly systems on demand and improve their effectiveness.