In our vision, all Swiss supply chains of temperature-controlled products are energy autonomous. To achieve energy autonomy, transparency is needed as to where energy is used in the supply chain. Additionally, knowledge is needed of which energy efficiency measures, energy recuperation and production measures, and alternative technologies are available to save or even recuperate energy in the supply chain, before developing a simulation model to make informed decisions about possible redesigns of the supply chain or technological setup. The innovation content lies in the combination of simulation tool and network design. As novelty, the simulation model integrates all internal and external supply chain partners. The application aims at demonstrating that decentralised supply chains integrating several partners can go beyond the energy savings and lead to energy autonomy, which is discussed as impossible until now.