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Mass spectrometric analyses of DARPins

Description

DARPins (designed ankyrin repeat proteins) are repeat proteins which are developed as novel therapeutics. For identification and establishment of the physicochemical properties of the lead candidates, exact molecular masses and amino acid sequences are assessed using mass spectrometry. Also, molecules are investigated for post-translational modifications at formulation and storage conditions as well after exposure to stress conditions.

Key Data

Project status

completed, 12/2019 - 12/2021

Institute/Centre

Institute of Chemistry and Biotechnology (ICBT)

Funding partner

Third party