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Process development for COVID-19 VLP vaccine production

Description

The project focuses on the development of a fermentation process for the production of a COVID-19 virus-like particle-based vaccine. Based on a shake flask process, the scale-up to stirred bioreactors is carried out up to pilot scale. The accompanying process analytics are used to assess cell growth and product formation, taking into account the influence of the culture media composition.

Key Data

Projectlead

Prof. Dr. Dieter Eibl

Deputy Projectlead

Project team

Sebastian Eberle, Géraldine Gubser, Rüdiger Maschke, Dr. Jan Ott, Cedric Schirmer, Dr. Stefan Seidel, Yannick Senn, Sandra Steiner, Misha Teale

Project status

completed, 04/2020 - 12/2020

Funding partner

Third party

Project budget

140'000 CHF