Process development for COVID-19 VLP vaccine production
Description
The project focuses on the development of a fermentation process for the production of a COVID-19 virus-like particle-based vaccine. Based on a shake flask process, the scale-up to stirred bioreactors is carried out up to pilot scale. The accompanying process analytics are used to assess cell growth and product formation, taking into account the influence of the culture media composition.
Key Data
Projectlead
Prof. Dr. Dieter Eibl
Deputy Projectlead
Project team
Sebastian Eberle, Géraldine Gubser, Rüdiger Maschke, Dr. Jan Ott, Cedric Schirmer, Dr. Stefan Seidel, Yannick Senn, Sandra Steiner, Misha Teale
Project status
completed, 04/2020 - 12/2020
Funding partner
Third party
Project budget
140'000 CHF