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School of Life Sciences
and Facility Management

Master's thesis

Applied Computational Life Sciences

The Master’s thesis is the scientific core of your studies. Through the thesis you not only demonstrate your knowledge and skills, but also the ability to successfully integrate into a research group and expand your knowledge in your specific field of scientific expertise.

Fields of Interest

Master’s Thesis at Partner University

Partner University

Contact Topics / Field
Bioinformatics and System Biology University of Giessen, GermanyExchange ProgrammeWith the University of Giessen we have a SEMP contract (Swiss-European Mobility Programme) where you get financial support for the exchange. Jochen Blum
Theo Smits
Maria Anisimova
  • Microbial Bioinformatics:
    Genome annotation,
    Comparative genomics
  • High-throughput data analysis:
    Cloud-Computing / Big Data- Pipeline / Workflow-Development,
    Research data management
  • Algebraic dynamic programming:
    Microbiome data analysis
  • Data Science Departement Worcester Polytechnic Institute WPI, USA Exchange Programme

    The WPI is an official partner university of ZHAW.

    For more information, please visit our website for the international exchange options or contact Dr. Matthias Nyfeler, the head of the ACLS Master's programme.

     

    Bioinformatics

    Research Group

    Contact Topics / Field
    Computational Genomics (ICLS) Maria Anisimova
  • Machine learning for genomics and medicine
  • Translational bioinformatics (ZHAW entrepreneurship Pilot)
  • Stochastic modeling, simulation, hypothesis testing
  • Genome evolution and phylogeny
  • Environmental Genomics and
    Systems Biology (IUNR)
    Theo Smits
  • Genomics, transcriptomics
  • Population genetics
  • Phylogenomics and Taxonomy
  • Antibiotic resistances
  • Plasmids
  • Source-tracking of human and plant pathogenic bacteria
  • Applications in biotechnology, medical microbiology,
    food science, environment and agriculture
  • Microbiome data analysis
  • Biomedical String Analysis (ICLS)

    Computational Genomics (ICLS) Tugçe Bilgin Sonay
  • Evolutionary population genomics
  • Transcriptomics, epigenetics and gene regulation
  • Data analysis and biostatistics
  • DNA and mutations
  • Machine learning approaches
  •    

    Computational Chemistry

    Research Group

    Contact Topics / Field
    Section for Organic and
    Medicinal Chemistry (ICBT)
    Stefan Höck
  • Cheminformatics
  • Pure functional programming
  • Type-driven development
  • Developing algorithms and designing
    abstractions in cheminformatics in tactically
    typed, purely functional programming languages
    (i.e. Haskell)
  • Applied Mathematics and Physics (IAMP)

    Biotechnological Processes

    Research Group

    Contact Topics / Field
    Centre for Analytical Chemistry (ICBT) Caspar Demuth
  • Development and application of sensors)
    for bioprocesses
  • Online bioprocess analytics
  • Characterisation of sensor components
  • Centre for Biocatalysis, Environmental-
    and Process-Technology (ICBT)

    Digital Health, Biology and Neuroscience

    Research Group

    Contact Topics / Field
    Biomedical Simulation (ICLS) Sven Hirsch
  • Understanding biomedical phenomena
  • Medical imaging analysis & diagnostics systems
  • Data assimilation and machine intelligence
  • Sensor and time series analysis
  • Simulations of brain aneurysms
  • Medical Image Analysis & Data Modeling (ICLS)

    Computational Genomics (ICLS) Maria Anisimova
  • Multi-omics for disease biomarker discovery
  • AI and cancer genomics for patient stratification
  • Microbiome-based biomarkers
  • HIV evolutionary dynamics
  • Computational Genomics (ICLS) Tugçe Bilgin Sonay
  • Cancer genomics and mutations
  • Omics on patient data
  • Medical data analysis
  • Immunotherapy
  •    

    Applications in Food Industry

    Research Group

    Contact Topics / Field
    Simulation & Optimization (ICLS) Lukas Hollenstein
  • Modelling, simulation and optimization of
    complex processes in production
  • Logistics, supply-chain, business, facilities, etc.
    using discrete-event simulation and data analytics
  • Food Microbiology Research Group (ILGI)

    Applications in Environment and Agriculture

    Research Group

    Contact Topics / Field
    Geoinformatics research group (IUNR) Patrick Laube
  • GIS, Geographic information Science and Geoinformatics
  • Computational Movement Analysis and Mobility Analytics
  • Remote Sensing (Satellite – Airplane - Drone)
  • Landscape Analytics / Dynamics
  • Spatial algorithms
  • Spatio-temporal data science
  • Spatio-temporal Environment Analysis
  • Spatio-temporal Environment Analysis
  • Natural Hazard Assessment
  • Cognitive Computing in Life Sciences (ICLS)
    Collaboration with Intel

    Master Thesis Topics with Full Description

    The table above lists thesis supervisors and their fields of interest. All these supervisors provide thesis topics. You can get in touch with them to learn more about their topics. In the following you find a small selection of topics with full description:

    Moisture Prediction – Curve Fitting(PDF 103,4 KB), Supervisor: Matthias Nyfeler (ICLS)

    Bioinformatics and the Microbiome(PDF 65,6 KB), Supervisor: Theo Smits (IUNR)

    Antimicrobial resistance prediction from MALDI-TOF mass spectra,(PDF 174,2 KB) Supervisor: Stefan Glüge (ICLS)

    Differentiation of bone marrow cell morphologies using deep neural networks(PDF 179,0 KB), Supervisor: Stefan Glüge (ICLS)

    Effect-based Trace Analytics of Toxic Substances leveraging Native Cloud Computing Services (Cognitive Services, AI and ML)(PDF 499,9 KB), Supervisor: Andreas Schönborn (INUR)

    Exploring the effectiveness of cancer-immunotherapies for non-small lung cancer(PDF 527,0 KB), Supervisor: Victor Garcia (ICLS)

    How does an ancient protein expression regulation mechanism affect how the choice of codons in DNA(PDF 502,5 KB), Supervisor: Victor Garcia (ICLS)

     

    Industry Collaborations

    Depending on your topic, you work in a research group at the ZHAW in Wädenswil or externally with an industrial or research partner. In any case, you have a local thesis advisor at ZHAW. Ask our advisors about possible industry collaborations. In the thesis Market-Place you find a list with some possible thesis topics and collaboration partners.

    Completed Master Theses

    Year of Graduation Student Title Advisor
    2019 Delucchi Matteo Tandem Repeat Variation in Genomic Databases Maria Anisimova (ZHAW, ICLS)
    2019 Gygax Gregory Smart Algorithms for Efficient Yield Forecasting Thomas Ott (ZHAW, ICLS)
    2019 Kaufmann Moritz Evolution of multidrug resistance in pEL60 plasmids Theo Smits (ZHAW, IUNR)
    2019 Meier Patrick A mathematical model to describe the relationship between the unfolded protein response (UPR) and production of recombinant proteins in the yeast Pichia pastoris Sven Hirsch (ZHAW, ICLS)
    2019 Naef Paulina Optimizing of the Tandem Repeat Annotation Library (TRAL) and Copy Number Variations of Tandem Repeats in RNAseq Illumina Data Maria Anisimova (ZHAW, ICLS)
    2019 Peechatt Jithin Mathew Characterisation of Bias and Variance of Progressive Sequence Alignment Manuel Gil (ZHAW, ICLS)
    2019 Schiling Daniel Geoinformatics methods for a better understanding of wildlife-caused traffic accidents in the Cantons of Zurich (Switzerland) Patrick Laube (ZHAW, IUNR)
    2019 Selvaratnam Laksathan Understanding cerebrovascular pathologies within the Circle of Willis using 0D flow network simulations Sven Hirsch (ZHAW, ICLS)
    2019 Siegrist Jonas Aaron Genome mining of polyketide and nonribosomal peptide synthases in actinomycetes Martin Sievers (ZHAW, ICBT)
    2019 Ta Cam Phuong Estimating Insertion and Deletion Parameters from Pairwise Sequence Alignments Manuel Gil (ZHAW, ICLS)
    2019 Weichart Sonja Continued development of an online application for the use in microbial batch cultures: Planning and simulation of experiments and data analysis and management Robert Vorburger (ZHAW, ICLS)
    2020 Atilgan Cahit Synthetic health data generation with pre- and intraoperative Total Knee Arthroplasty (TKA) parameters for ligament balancing and subsequent outcome analysis Daniel Baumgartner (ZHAW)
    2020 Joseph Abel Thomson Design of Algorithms to study the property of Reversibility in TKF91 Model Manuel Gil (ZHAW, ICLS)
    2020 Mikos Alexander A Perception-based Adaptive Immune System Model to describe the Effect of Anticancer Radiation Therapy In-Silico Stefan Scheidegger (ZHAW, SoE)
    2020 Müller Georg Simulation of Renewable and Self-Sufficient Building Energy Ivo Kälin (ZHAW, ICLS)
    2020 Nüesch Manuel Simulation of separation tasks using vacuum distillation Simone Ulzega (ZHAW, ICLS)
    2020 Poulose Eldhose A study of dynamics of Indels using ProPIP, PRANK and MAFFT Manuel Gil (ZHAW, ICLS)
    2020 Seidel Stefan Gas bubble simulation for the computation of oxygen supply for cells Werner Sören (ZHAW, ICBT)
    2020 Brühwiler Robin Stochastic Optimization of Time-Dose-Fractionation Schemes in Cancer Radiation Therapy Sven Hirsch (ZHAW, ICLS)
    2021 Antalfy Imre Istvàn A Data Science Approach to Solid Waste Biogas Plats Data Pre-processing and Modelling with Neural Networks Martin Schüle (ZHAW, ICLS)
    2021 Chandra Saurabh Analysis of health conditions of cancer patients in palliative care based on movement data tracked by wearable devices Thomas Ott (ZHAW, ICLS)
    2021 Mauch Ueli Modelling tick risk from uncertain citizen science data. Exploring the benefits of irregular spatial tessellations Patrick Laube (ZHAW, ICLS)
    2021 Krayer Patricia Modelling Environmental and Nutritional Impacts of Vegan Agriculture Matthias Nyfeler (ZHAW, ICLS)
    2021 Rey Sofia Health Status Analysis from Wearable Children Patient Data Sven Hirsch (ZHAW, ICLS)
    2021 Roth Sandro AngioSynth - Cross-modality synthesis of cerebral angiographies using CycleGANs Norman Juchler (ZHAW, ICLS)
    2021 Schmutz Stefan Characterizing undetermined sequences from metagenomic sequencing Maria Anisimova (ZHAW, ICLS)
    2021 Von Gunten Cédric Public sequencing data mining and in silico protein masses prediction for improving accurate subspecies determination in Bacillus cereus using MALDI-TOF MS Jöel Pothier (ZHAW, IUNR)
    2021 Von Rotz Sebastian Evaluation and development of a bioinformatics workflow for amplicon sequencing with nanopore long read technology Jöel Pothier (ZHAW, IUNR)
    2021 Wegmann Thomas Computer Vision for the Automated Validation of Cancer Drugs Robert Vorburger (ZHAW, ICLS)
    2021 Wrobel Anna Prediction of parturition in mares based on body sensor data Thomas Ott (ZHAW, ICLS)
    2022 Amacker Julian Martin Analysis of brain connectivity using phase transfer entropy and deep learning based causal inference Sven Hirsch (ZHAW, ICLS)
    2022 Bajka Daniel Extraction and Provision of Tacit Knowledge from Institutions Data Repositories on Energy Research Christian Glahn (ZHAW, ICLS)
    2022 Gees Marco Investigation of the Gene Expression Level for CODON Optimized Heterologous Genes Christin Peters (ZHAW, ICLS)
    2022 Graf Dominik Automatic interpretation of NMR Spectra using Neural Networks Martin Schüle (ZHAW, ICLS)
    2022 Grossenbacher Amira Transition analysis of small-scale and at-scale Chromatography Columns Olivier Merlo (ZHAW, ICLS)
    2022 Höhener Rebecca Juliette Applying Reinforcement Learning to a Production Scheduling Problem Lukas Hollenstein (ZHAW, ICLS)
    2022 Iglhaut Clara Ev Andrea Indel-Aware Parsimony Methods for Phylogenetic Inferences Manuel Gil (ZHAW, ICLS)
    2022 Joos Matthias Optimization of the Delirium Algorithm Workflow of the University Hospital of Zurich with Data Analytics and Machine Learning Thomas Ott (ZHAW, ICLS)
    2022 Jordan Sara Community analysis of methanogenic microbiomes in biogas reactors Theo Smits (ZHAW, IUNR)
    2022 Keel Thomas Modeling the aging behavior of electrochemical sensors Caspar Demuth (ZHAW, ICLS)
    2022 Memeti Nurdzane The CRISPR region analysis program (CRAP) Theo Smits (ZHAW, IUNR)
    2022 Schaub Lukas Cell growth and lifelines analysis CFD Solver Implementation Dieter Eibl (ZHAW, ICLS)
    2022 Senn Saskia Ensemble of BERT Variants for Depression Detection Claus Horn (ZHAW, ICLS)
    2022 Thomas Chirayil Harry Evaluation of Transfer Learning for Protein Function Prediction Claus Horn (ZHAW, ICLS)
    2022 Von Däniken Kim Generating synthetic order data from clinical laboratories using classical methods of statistics and machine learning Lukas Hollenstein (ZHAW, ICLS)
    2022 Walder Tim Application of data exploration algorithms on a labelled property graph Robert Vorburger (ZHAW, ICLS)
    2023 Baiges Samuel Polypharmacy Analysis in Delirium ICU Patients Stefan Glüge (ZHAW, ICLS)
    2023 Benvenga Vanni Food Pathogen Metagenomics Theo Smits (ZHAW, IUNR)
    2023 Berger Thomas Advanced Spectroscopic Analysis and Data Exploitation Concepts in Bioprocessing Lukas Neutsch (ZHAW, ICBT)
    2023 Bertoz Marc Oliver Deep Learning for Vortex Detection and Tracking in Cardiac MRI Robert Vorburger (ZHAW, ICLS)
    2023 Biland Julien Exploratory Analysis of Peripheral Neuropathy Patient Biomarker and Symptom Characteristics Norman Juchler (ZHAW, ICLS)
    2023 Bourtzos Anastasuios Bayesian inference for skeletal muscle structure and perfusion estimation from magnetic resonance imaging Georg Spinner (ZHAW, ICLS)
    2023 Breitenmoser Linus Automatic creation and selection of mechanistic models of cell culture processes in bioprocess engineering Lukas Neutsch (ZHAW, ICBT)
    2023 Bürkli Tim Electric Power prediction of a waste incineration plant using machine & deep learning Robert Vorburger (ZHAW, ICLS)
    2023 Gericke Eric Flood Modeling With Neural Cellular Automata Martin Schüle (ZHAW, ICLS)
    2023 Graber David Protein Interaction Prediction with Graph Convolutional Networks and AlphaFold-predicted Protein Structures Claus Horn (ZHAW, ICLS)
    2023 Grossmann Leonie Automated Quantification of Histological Constituents in Thrombosed Aneurysms Norman Juchler (ZHAW, ICLS)
    2023 Imstepf Nicolas Re-Programming of Fe(II)/α-Ketoglutarate-Dependent Hydroxylases to Halogenases Rebecca Buller (ZHAW, ICBT)
    2023 Koch Kilian Deep learning assisted X-ray photoelectron spectroscopy analysis Martin Schüle (ZHAW, ICLS)
    2023 Kunz Domink AI-based patient identity verification for radio-therapeutic 3D cone beam computed tomography Norman Juchler (ZHAW, ICLS)
    2023 Maslov Dmitry Federated Learning for Speech Processing on the Edge: Practical Implementation and Considerations for Reducing Network Bandwidth Requirements of Voice-Aware Edge Computing Applications Christian Glahn (ZHAW, ICLS)
    2023 Maurer Manuel Data driven analysis of Fluorescence Spectroscopy of Algae as a compound monitoring tool in Bioprocesses Lukas Neutsch (ZHAW, ICBT)
    2023 Medici Milo Data Framework to Characterize and Identify Wildlife Corridors Robert Vorburger (ZHAW, ICLS)
    2023 Mohammad Yar Kevin Machine-learning assisted engineering of a Fe(II)/αKG-dependent Hydroxylase to accept lignin derivatives Rebecca Buller (ZHAW, ICBT)
    2023 Orbeanu Georgiana Evaluation of Deep Neural Networks for Haematology Image Classification Stefan Glüge (ZHAW, ICLS)
    2023 Rey Phil Automatic spinal canal segmentation on axial spine MRI images using a U-Net CNN Georg Spinner (ZHAW, ICLS)
    2023 Rieder Jonathan Applied Machine Learning Algorithms for automated Flow Cytometry Data Evaluation Lukas Neutsch (ZHAW, ICBT)
    2023 Saxer Jasmin Ontology-Aware Biomedical Text Classification Ahmad Aghaebrahimian (ZHAW, ICLS)
    2023 Schittly Timo Dynamic modelling of nitrogen flow through fish gut to estimate nitrogen excretions Dominik Refardt (ZHAW, IUNR)