26.02.21

A Ketoreductase Library for the Synthesis of Pharmaceutical-relevant Alcohols

Off-the-shelf enzyme libraries allow fast screening for suitable readily available biocatalyst candidates and thus increase the competitiveness of biocatalytic reaction steps in chemical process development.

16.02.21

Master of Science FH Prize 2020 for Sandro Giger

Sandro Giger was awarded the Master of Science FH Prize 2020 of the Schweizerischer Verband dipl. Chemiker FH (SVC).

16.12.20

Biocatalysis in the Swiss Manufacturing Environment

How has the biocatalysis situation in Switzerland evolved within the last four years and what could be the contribution of biocatalysis to address current societal challenges?

30.11.20

Strategies to reduce mycotoxins in grain side product streams

Mycotoxin contamination in feed and food is a major health treat and new strategies to lower their content are necessary.

14.10.20

ZHAW-Forschende trainieren Enzym, das Plastik zersetzt

Das Enzym «PETase» kann Plastik abbauen, ist aber nicht sehr produktiv. ZHAW-Forschende trainieren das Enzym deshalb mittels «gerichteter Evolution», damit es künftig zum Trinkwasseraufbereiten oder Biorecycling genutzt werden kann. Maschinelles…

30.09.20

New INNOSUISSE project: Biocatalytic halogenation for the sustainable development of agrochemicals

We are happy to announce our new INNOSUISSE project in collaboration with Syngenta for the sustainable development of agrochemicals.

05.03.20

The Ene-Reductase Toolbox is growing

Ppo-Er1, a further member to the newly identified subgroup III of the old yellow enzyme family is characterized in our recent publication “Characterization of the Novel Ene Reductase Ppo-Er1 from Paenibacillus Polymyxa” in “Catalysts”.

29.01.20

Exploring the biocatalytic potential of Fe/α-ketoglutaratedependent halogenases

a review by Mortiz Voss, Sumire Honda Malca and Rebecca Buller accepted for publication at "Chemistry - A European Journal".

13.01.20

The Laboratory of Biocatalysis participates in the new National Centre of Competence in Research “Suchcat”

“Suchcat” led by Prof. Javier Pérez-Ramírez (ETHZ) and Prof. Jérôme Waser (EPFL) tries to find new ways to make chemical production more sustainably. The group of Prof. Rebecca Buller will contribute by developing respective biocatalysts.

10.01.20

Review on Flavin-Dependent Halogenase Biocatalysis accepted in "Catalysts"

“Recent Advances in Flavin-Dependent Halogenase Biocatalysis: Sourcing, Engineering, and Application” a review written by Johannes Büchler, Athena Papadopoulou and Rebecca Buller is now available in “Catalysts”.

08.10.19

Publication in «Angewandte Chemie»

«Evolved Aliphatic Halogenases Enable Regiocomplementary C‐H Functionalization of an Added‐Value Chemical» is accepted for publication in «Angewandte Chemie»

24.09.19

Enzymatic PET Degradation

«Enzymatic PET Degradation» a review article by Athena Papadopoulou, Katrin Hecht and Rebecca Buller is part of special issue on Green and Sustainable Chemistry (Chimia 73 (2019) 743–749).

29.08.19

Microbial Epimerases: A toolbox for the synthesis of novel peptide-based drugs

Antibiotic resistance has increased steadily in recent years. Could peptides - organic chemical compounds made up of amino acids - contribute to the solution?

07.03.19

New Innosuisse Funding

Christin Peters together with Prof. Donald Hilvert (ETH) and Prof. Mark Tibbitt (ETH) received funding within Innosuisse «Manufacturing technologies» impulse programme (Projekt 35545.1 IP-LS)

14.02.19

Publication in CHEMBIOCHEM

Additional ene reductases have been added to our biocatalytic toolbox! For more information check «Novel Old Yellow Enzyme Subclasses» just published in CHEMBIOCHEM.

19.12.18

Bookchapter in «Pharmaceutical Biocatalysis»

«Ene Reductases in Pharmaceutical Chemistry» a bookchapter for «Pharmaceutical Biocatalyis» (Pan Stanford Publishing), contributed by Katrin Hecht and Rebecca Buller is accepted for publication

19.12.18

Review in Current Opinion in Biotechnology

«Directed Evolution of Carbon-Hydrogen Bond Activating Enzymes» a review by Raphael Frey, Takahiro Hayashi and Rebecca Buller is accepted for publication at «Current Opinion in Biotechnology».

27.02.18

Collaboration with Novartis Pharma AG

«Biocatalytic oxidation processes with alpha-ketoglutarate dependent enzymes for sustainable chemical synthesis» with Partner Novartis Pharma AG was approved by the CTI (CTI 28385.1 PFLS-LS)

26.02.18

Rebecca Buller will speak at the SwissCat Seminar «Catalysis Across Scales»

«Harnessing nature: biocatalysis for development and drug discovery» is the title of the talk

19.02.18

CHIMIA article on «Innovation in Biocatalysis – A Swiss Network Project Coordinated by the Competence Center for Biocatalysis (CCBIO)»

The project «Innovation in Biocatalysis» aims to create a network for dynamic and innovative biocatalysis in Switzerland.